Across TCGA pan-cancer cohorts, MIR1827 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MIR1827’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where MIR1827 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR1827 is over-expressed in tumor.
LUAD are the cancer types where MIR1827 tumor–normal differential expression is most reproducible.