Across TCGA pan-cancer cohorts, MIR181A1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MIR181A1 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MIR181A1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR181A1 expression acts as an unfavorable survival marker.

COAD and LIHC are the cancer types where MIR181A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	II,III,IV	0.056	0.851	<.001	18	view →
LIHC	OS	Median	All	0.188	0.669	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR181A1 tumor-vs-normal RNA expression · all MIR181A1 data types