Across TCGA pan-cancer cohorts, MIR16-2 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated MIR16-2 data layer.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIR16-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR16-2 expression acts as an unfavorable survival marker.
UCEC, BLCA, and THCA are the cancer types where MIR16-2 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.