Across TCGA pan-cancer cohorts, MIR154 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MIR154 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR154 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR154 expression acts as an unfavorable survival marker.

HNSC and COAD are the cancer types where MIR154 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.156	0.751	<.001	48	view →
COAD	OS	Median	All	0.168	0.806	.002	24	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR154 tumor-vs-normal RNA expression · all MIR154 data types