Across TCGA pan-cancer cohorts, MIR1537 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR1537’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR1537 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR1537 is over-expressed in tumor.
HNSC and STAD are the cancer types where MIR1537 tumor–normal differential expression is most reproducible.