Across TCGA pan-cancer cohorts, MIR141 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR141’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MIR141 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR141 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

BLCA, STAD, and LUAD are the cancer types where MIR141 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR141 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+0.837	<.001	5	view →
STAD	Male	All	+0.187	.023	2	view →
LUAD	All	II,III,IV	−0.293	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MIR141 RNA expression & survival · all MIR141 data types