Q-omics provides the consensus-scored MIR140 profile across patient tissues and cancer cell-line models. MIR140 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in CHOL. Among the 18 cancer types available for tumor–normal comparison, MIR140 is differentially expressed in 5, with the highest sampling consensus in KIRC. Additionally, MIR140 RNA expression shows 8,668 significant gene co-expression associations, with the highest sampling consensus in KIRC. Together, these results highlight CHOL, and KIRC as cancer lineages where MIR140 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR140 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR140 survival associations across molecular data types. MIR140 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR140 RNA expression–survival associations across cancer types. High MIR140 expression shows unfavorable associations in CHOL, LUSC, LIHC, UCS and TGCT, but favorable associations in KIRC. The CHOL Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CHOL as the clearest survival context for MIR140 RNA expression.
This table summarizes MIR140 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR140. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR140 shows lower tumor expression in KIRP, KICH and BRCA and higher tumor expression in KIRC and CHOL. The KIRC box plot shows higher MIR140 RNA expression in tumor versus normal tissue (log2 FC = +2.765, t-test p < 0.001).
This table shows molecular features associated with MIR140 in patient tissues and cancer cell lines. In patient samples, MIR140 shows the broadest associations at the RNA and protein expression levels, with KIRC recurring as the lineage with the largest associated feature set.
