Across TCGA pan-cancer cohorts, MIR1302-8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR1302-8’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR1302-8 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR1302-8 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
KIRC and LIHC are the cancer types where MIR1302-8 tumor–normal differential expression is most reproducible.