MIR1302-2HG

Across TCGA pan-cancer cohorts, MIR1302-2HG RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MIR1302-2HG data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher MIR1302-2HG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR1302-2HG expression acts as an unfavorable survival marker, although some lineages such as LGG and HNSC show a favorable association.

CHOL, DLBC, and THCA are the cancer types where MIR1302-2HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	II,III,IV	0.016	0.406	<.001	81	view →
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	81	view →
THCA	DFS	Tertile	IV	0.146	0.795	.004	42	view →
STAD	DFS	Tertile	II,III,IV	0.493	0.715	.040	27	view →
UCEC	DFS	Tertile	All	0.706	0.844	.023	24	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
UCS	OS	Tertile	IV	0.269	0.624	.042	18	view →
LAML	DFS	Quartile	All	0.213	0.543	.006	18	view →
PCPG	OS	Tertile	All	0.888	1.000	.002	18	view →
PRAD	DFS	Tertile	All	0.760	0.892	.018	18	view →
READ	DFS	Tertile	III,IV	0.176	0.768	<.001	18	view →
LGG	DFS	Tertile	All	0.928	0.802	.015	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MIR1302-2HG–CHOL (DFS)

Open the CHOL breakdown →