Across TCGA pan-cancer cohorts, MIR128-2 RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated MIR128-2 data layer.

The strongest signal is observed in acute myeloid leukemia (LAML), where higher MIR128-2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR128-2 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

LAML, STAD, and LGG are the cancer types where MIR128-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LAML	DFS	Quartile	All	0.582	0.302	.001	50	view →
STAD	DFS	Tertile	All	0.501	0.668	.027	18	view →
LGG	OS	Quartile	All	0.737	0.844	.003	17	view →
GBM	OS	Tertile	All	0.313	0.467	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR128-2 tumor-vs-normal RNA expression · all MIR128-2 data types