Across TCGA pan-cancer cohorts, MIR1276 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR1276’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where MIR1276 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR1276 is over-expressed in tumor, although a few such as STAD and KICH show the opposite, repressed pattern.
STAD, CHOL, and KICH are the cancer types where MIR1276 tumor–normal differential expression is most reproducible.