MIR1270

Across TCGA pan-cancer cohorts, MIR1270 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MIR1270 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher MIR1270 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR1270 expression acts as an unfavorable survival marker.

ESCA, SARC, and BLCA are the cancer types where MIR1270 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.103	0.868	<.001	18	view →
SARC	DFS	Median	All	0.024	0.611	<.001	6	view →
BLCA	OS	Median	III,IV	0.187	0.684	.006	6	view →
COAD	DFS	Median	II,III,IV	0.225	0.654	.001	6	view →
GBM	OS	Median	All	0.160	0.418	.026	3	view →
HNSC	DFS	Median	All	0.206	0.628	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MIR1270–ESCA (OS)

Open the ESCA breakdown →