MIR1266

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR1266 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR1266 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MIR1266 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR1266 expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

MESO, THCA, and KIRC are the cancer types where MIR1266 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileIV0.0360.602<.001126view →
THCAOSTertileII,III,IV0.5790.988<.00160view →
KIRCDFSTertileIV0.0830.641<.00154view →
BLCAOSTertileIV0.0740.590<.00136view →
LGGOSTertileAll0.2040.799<.00136view →
HNSCDFSTertileAll1.0000.315.02524view →
OVOSTertileIV0.8470.558.04118view →
BRCADFSTertileIII,IV0.8560.450.03712view →
LUADOSTertileAll0.7480.314.0236view →
SKCMOSTertileAll1.0000.331.0363view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration