Across TCGA pan-cancer cohorts, MIR1262 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR1262’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR1262 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR1262 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.
HNSC, KIRP, and KICH are the cancer types where MIR1262 tumor–normal differential expression is most reproducible.