Across TCGA pan-cancer cohorts, MIR1250 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR1250’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR1250 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR1250 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, KIRC, and LUAD are the cancer types where MIR1250 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR1250 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.323	<.001	5	view →
KIRC	Female	III,IV	+0.237	.044	3	view →
LUAD	All	II,III,IV	−0.357	.014	2	view →
ESCA	All	All	−0.337	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR1250 RNA expression & survival · all MIR1250 data types