Across TCGA pan-cancer cohorts, MIR1249 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of MIR1249’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR1249 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR1249 is over-expressed in tumor.
KIRC, HNSC, and STAD are the cancer types where MIR1249 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR1249 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.