Q-omics provides the consensus-scored MIR122HG profile across patient tissues and cancer cell-line models. MIR122HG expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, MIR122HG is differentially expressed in 7, with the highest sampling consensus in KIRC. Additionally, MIR122HG RNA expression shows 7,234 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight ACC, KIRC, and TGCT as cancer lineages where MIR122HG shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR122HG — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR122HG survival associations across molecular data types. MIR122HG RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR122HG RNA expression–survival associations across cancer types. High MIR122HG expression shows unfavorable associations in ACC, LUSC, MESO, READ, LUAD and GBM. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for MIR122HG RNA expression.
This table summarizes MIR122HG tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR122HG. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR122HG shows lower tumor expression in COAD, KICH and CHOL and higher tumor expression in KIRC, LUAD and LUSC. The KIRC box plot shows higher MIR122HG RNA expression in tumor versus normal tissue (log2 FC = +0.371, t-test p < 0.001).
This table shows molecular features associated with MIR122HG in patient tissues and cancer cell lines. In patient samples, MIR122HG shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
