MIR1185-1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR1185-1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MIR1185-1 data layer compared with 10 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MIR1185-1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR1185-1 expression acts as an unfavorable survival marker.

BRCA and SKCM are the cancer types where MIR1185-1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSMedianAll0.2870.924<.00136view →
SKCMDFSMedianAll0.0460.738<.0016view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration