MIPOL1

Across TCGA cell cohorts, MIPOL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,331 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MIPOL1-associated GO terms across cancer lineages are Aminoacyl-tRNA metabolism involved in translational fidelity, Positive regulation of translation, and Alpha-ketoglutarate transport. Each is linked with MIPOL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both MIPOL1-to-partner and partner-to-MIPOL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aminoacyl-tRNA metabolism involved in translational fidelity grouped by MIPOL1-low versus MIPOL1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIPOL1→partner) and Y-score (partner→MIPOL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.111	+1.017	.001	.001	3	9
LARGE_INTESTINE	Positive regulation of translation →	+0.053	+1.507	<.001	<.001	3	9
CNS	Alpha-ketoglutarate transport →	-0.365	-1.435	<.001	<.001	3	8
BLOOD_Leukemia	Regulation of translational fidelity →	+0.042	+0.740	.006	.005	3	8
OVARY	Microtubule polymerization →	+0.070	+0.790	.009	.005	3	8
BREAST	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.077	+0.595	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,331 associations by consensus.

Aminoacyl-tRNA metabolism involved in translational fidelity by MIPOL1 expression — BONE

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