MIPEPP3

Across TCGA pan-cancer cohorts, MIPEPP3 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MIPEPP3 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher MIPEPP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIPEPP3 expression acts as an unfavorable survival marker, although some lineages such as LAML and PAAD show a favorable association.

CESC, LAML, and BLCA are the cancer types where MIPEPP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	III,IV	0.466	0.950	<.001	74	view →
LAML	DFS	Tertile	All	0.560	0.226	<.001	46	view →
BLCA	DFS	Median	All	0.135	0.488	.002	40	view →
PAAD	OS	Tertile	All	0.502	0.250	.001	28	view →
LIHC	OS	Tertile	All	0.690	0.836	.004	26	view →
READ	OS	Median	III,IV	0.734	0.310	.005	22	view →
ACC	DFS	Tertile	All	0.266	0.693	.001	19	view →
MESO	OS	Median	III,IV	0.781	0.301	.003	15	view →
THYM	DFS	Quartile	II,III,IV	1.000	0.455	.015	14	view →
LGG	DFS	Quartile	All	0.359	0.511	.022	13	view →
COAD	DFS	Quartile	All	0.554	0.776	.007	11	view →
KIRP	DFS	Quartile	All	0.952	0.711	.031	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MIPEPP3–CESC (DFS)

Open the CESC breakdown →