MIP

Across TCGA patient cohorts, MIP protein abundance is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MIP-associated genes across cancer lineages are RAB36, TLDC2, and SAMHD1. Each is linked with MIP in more than 1 cancer types. Because this analysis shows association rather than direction, both MIP-to-partner and partner-to-MIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIP versus RAB36 in BRCA, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIP→partner) and Y-score (partner→MIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAB36 →	+1.818	+1.748	.002	.006	3	1
BRCA	TLDC2 →	+0.365	+1.748	.005	.006	3	1
BRCA	SAMHD1 →	+1.130	+2.187	.003	.006	3	1
BRCA	PPP1R16B →	+2.346	+2.326	<.001	.001	3	1
BRCA	SYT17 →	+1.871	+1.988	.001	<.001	3	1
BRCA	PARP11 →	+1.311	+1.988	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

MIP vs RAB36 — BRCA

Explore this scatter interactively →