MIP

Across TCGA patient cohorts, MIP protein abundance is significantly associated with the protein abundance of many other proteins, with 316 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MIP-associated proteins across cancer lineages are RAI14_S318, RASGRP2_S587, and LRCH4_S281. Each is linked with MIP in more than 1 cancer types. Because this analysis shows association rather than direction, both MIP-to-partner and partner-to-MIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIP versus RAI14_S318 in BRCA, with a Pearson correlation of -0.83.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIP→partner) and Y-score (partner→MIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAI14_S318 →	-2.199	-2.219	<.001	.001	3	1
BRCA	RASGRP2_S587 →	+1.769	+2.077	<.001	<.001	3	1
BRCA	LRCH4_S281 →	+0.759	+1.724	.002	.002	3	1
BRCA	LSM2_S65 →	+0.732	+1.776	.002	.001	3	1
BRCA	TMCO4 →	+0.727	+2.445	.002	.001	3	1
BRCA	TNC_S72 →	-1.723	-1.761	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 316 associations by consensus.

MIP vs RAI14_S318 — BRCA

Explore this scatter interactively →