MINPP1

Across TCGA pan-cancer cohorts, MINPP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MINPP1 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MINPP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MINPP1 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where MINPP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.448	0.832	.001	45	view →
CCRCC	OS	Median	II,III,IV	0.339	1.000	.003	20	view →
PDAC	OS	Tertile	All	0.276	0.543	.016	11	view →
GBM	OS	Median	All	0.674	0.367	.007	8	view →
HNSC	OS	Tertile	II,III,IV	0.653	0.833	.031	5	view →
LSCC	OS	Median	II,III,IV	1.000	0.833	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MINPP1–LUAD (DFS)

Open the LUAD breakdown →