MINDY4

Across TCGA cell cohorts, MINDY4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,127 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MINDY4-associated GO terms across cancer lineages are Protein localization to vacuole, Pre-mRNA catabolic process, and Cilium movement. Each is linked with MINDY4 in more than 10 cancer types. Because this analysis shows association rather than direction, both MINDY4-to-partner and partner-to-MINDY4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to vacuole grouped by MINDY4-low versus MINDY4-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MINDY4→partner) and Y-score (partner→MINDY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Protein localization to vacuole →	+0.047	+0.857	<.001	<.001	3	11
KIDNEY	Pre-mRNA catabolic process →	+0.131	+0.763	<.001	<.001	3	10
SKIN	Cilium movement →	-0.058	-1.183	<.001	<.001	3	9
SOFT_TISSUE	Cilium or flagellum-dependent cell motility →	-0.067	-0.998	<.001	<.001	3	8
SOFT_TISSUE	Cilium-dependent cell motility →	-0.067	-0.998	<.001	<.001	3	8
OVARY	Meiotic mismatch repair →	+0.095	+0.886	.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,127 associations by consensus.

Protein localization to vacuole by MINDY4 expression — CNS

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