MINDY2

Across TCGA patient cohorts, MINDY2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,534 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MINDY2-associated genes across cancer lineages are IRAG1, TIMP3, and MEIS3. Each is linked with MINDY2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MINDY2-to-partner and partner-to-MINDY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MINDY2 versus IRAG1 in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MINDY2→partner) and Y-score (partner→MINDY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IRAG1 →	+1.147	+0.287	<.001	<.001	3	7
CCRCC	TIMP3 →	+1.424	+0.268	<.001	<.001	3	6
UCEC	MEIS3 →	+1.123	+0.271	<.001	<.001	3	6
OV	AOC3 →	+1.157	+0.245	<.001	.001	3	6
OV	EDNRA →	+1.599	+0.476	<.001	<.001	3	6
BRCA	COLEC12 →	+1.084	+0.404	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,534 associations by consensus.

MINDY2 vs IRAG1 — OV

Explore this scatter interactively →