MINDY2

Across TCGA patient cohorts, MINDY2 mutation is significantly associated with the RNA expression of many other genes, with 759 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MINDY2-associated genes across cancer lineages are RNA5SP432, RNA5SP198, and VTRNA2-2P. Each is linked with MINDY2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MINDY2-to-partner and partner-to-MINDY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP432 grouped by MINDY2-low versus MINDY2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MINDY2→partner) and Y-score (partner→MINDY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP432 →	+0.255	+4.539	.001	.008	3	2
CESC	RNA5SP198 →	+0.284	+5.144	<.001	.003	3	2
CESC	VTRNA2-2P →	+0.430	+4.601	<.001	.004	3	2
OV	RNU2-41P →	+0.182	+5.297	.004	.006	3	2
OV	LINC02425 →	+1.271	+4.991	<.001	.009	3	2
LUAD	OR8Q1P →	+0.352	+4.157	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 759 associations by consensus.

RNA5SP432 by MINDY2 expression — CESC

Explore this box plot interactively →