MINDY1

Across TCGA pan-cancer cohorts, MINDY1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MINDY1 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MINDY1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated MINDY1 expression acts as an unfavorable survival marker.

HNSC, SKCM, and GBM are the cancer types where MINDY1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.078	0.710	<.001	24	view →
SKCM	DFS	Median	III,IV	0.507	0.613	<.001	10	view →
GBM	DFS	Median	All	0.048	0.242	.006	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MINDY1–HNSC (DFS)

Open the HNSC breakdown →