MINDY1

Across TCGA pan-cancer cohorts, MINDY1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MINDY1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MINDY1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MINDY1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

COAD, LSCC, and HNSC are the cancer types where MINDY1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.879	1.000	.037	12	view →
LSCC	DFS	Quartile	II,III,IV	0.773	1.000	.020	8	view →
HNSC	DFS	Median	All	0.860	0.361	.022	6	view →
LUAD	DFS	Quartile	II,III,IV	0.709	0.942	.037	4	view →
PDAC	DFS	Tertile	III,IV	0.576	0.744	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MINDY1–COAD (DFS)

Open the COAD breakdown →