MINDY1

Across TCGA cell cohorts, MINDY1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MINDY1-associated genes across cancer lineages are C9orf92, SLC5A8, and PF4. Each is linked with MINDY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MINDY1-to-partner and partner-to-MINDY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf92 grouped by MINDY1-low versus MINDY1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MINDY1→partner) and Y-score (partner→MINDY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C9orf92 →	+0.194	+5.369	<.001	.004	3	1
SOFT_TISSUE	SLC5A8 →	+0.006	+4.930	<.001	.008	3	1
BLOOD_Lymphoma	PF4 →	+0.031	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP7-1 →	+0.031	+4.867	<.001	.009	3	1
LARGE_INTESTINE	HSFY2 →	+0.023	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

C9orf92 by MINDY1 expression — SOFT_TISSUE

Explore this box plot interactively →