MINAR1

Across TCGA patient cohorts, MINAR1 mutation is significantly associated with the RNA expression of many other genes, with 3,812 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MINAR1-associated genes across cancer lineages are EIF2B2, PDGFD, and GLRX5. Each is linked with MINAR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MINAR1-to-partner and partner-to-MINAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF2B2 grouped by MINAR1-low versus MINAR1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MINAR1→partner) and Y-score (partner→MINAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	EIF2B2 →	+0.434	+2.623	.001	.005	3	4
UCEC	PDGFD →	-0.658	-1.726	<.001	.006	3	4
SKCM	GLRX5 →	+0.328	+3.195	.005	.009	2	4
SKCM	BTBD6 →	+0.425	+2.613	.005	.005	3	3
UCEC	NOC2L →	+0.305	+1.491	.006	<.001	3	3
UCEC	LONP1 →	+0.671	+2.451	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,812 associations by consensus.

EIF2B2 by MINAR1 expression — SKCM

Explore this box plot interactively →