MINAR1

Across TCGA patient cohorts, MINAR1 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MINAR1-associated genes across cancer lineages are ATM, FoxM1, and Acetyl-a-Tubulin-Lys40. Each is linked with MINAR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MINAR1-to-partner and partner-to-MINAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by MINAR1-low versus MINAR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MINAR1→partner) and Y-score (partner→MINAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.491	-2.308	<.001	<.001	3	4
UCEC	FoxM1 →	+0.164	+1.169	.027	.017	3	3
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.742	+3.169	.003	.017	3	3
UCEC	MEK1 →	+0.274	+1.523	.009	.006	3	3
UCEC	eIF4E →	+0.122	+2.335	.044	.002	3	2
UCEC	ACC_pS79 →	+0.211	+0.999	.034	.042	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

ATM by MINAR1 expression — UCEC

Explore this box plot interactively →