MIGA1

Across TCGA pan-cancer cohorts, MIGA1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MIGA1 data layer compared with 27 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher MIGA1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIGA1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LSCC, LUAD, and PDAC are the cancer types where MIGA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.575	0.817	.002	12	view →
LUAD	DFS	Median	II,III,IV	0.796	0.295	<.001	9	view →
PDAC	DFS	Median	IV	0.255	0.741	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MIGA1–LSCC (DFS)

Open the LSCC breakdown →