MIGA1

Across TCGA cell cohorts, MIGA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,291 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MIGA1-associated GO terms across cancer lineages are Protein localization to vacuole, Golgi vesicle transport, and Cytosolic transport. Each is linked with MIGA1 in more than 16 cancer types. Because this analysis shows association rather than direction, both MIGA1-to-partner and partner-to-MIGA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to vacuole grouped by MIGA1-low versus MIGA1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIGA1→partner) and Y-score (partner→MIGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein localization to vacuole →	+0.083	+0.796	<.001	<.001	3	17
URINARY_TRACT	Golgi vesicle transport →	+0.046	+0.669	<.001	.003	3	16
CNS	Cytosolic transport →	+0.053	+0.579	<.001	.001	3	15
SKIN	Post-Golgi vesicle-mediated transport →	+0.049	+0.473	.003	.003	3	15
SOFT_TISSUE	Establishment of protein localization to vacuole →	+0.072	+0.710	<.001	<.001	3	15
LUNG_SCLC	Protein localization to lysosome →	+0.119	+0.947	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,291 associations by consensus.

Protein localization to vacuole by MIGA1 expression — LUNG_SCLC

Explore this box plot interactively →