MIER3

Across TCGA patient cohorts, MIER3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,045 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIER3-associated proteins across cancer lineages are DHX9, RPL7, and RPS6. Each is linked with MIER3 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIER3-to-partner and partner-to-MIER3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIER3 versus DHX9 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIER3→partner) and Y-score (partner→MIER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DHX9 →	+0.333	+0.544	<.001	<.001	3	5
GBM	RPL7 →	-0.333	-0.320	.001	.002	3	5
BRCA	RPS6 →	-0.422	-0.634	.002	.003	3	5
LSCC	SMAD4 →	+0.287	+0.444	<.001	<.001	3	5
BRCA	MYEF2_S17 →	+0.823	+0.641	<.001	<.001	3	5
GBM	WDFY4 →	-0.437	-0.415	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,045 associations by consensus.

MIER3 vs DHX9 — GBM

Explore this scatter interactively →