Across TCGA patient cohorts, MIER1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,417 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MIER1-associated proteins across cancer lineages are DR1, TRAP1, and SERPINB8. Each is linked with MIER1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIER1-to-partner and partner-to-MIER1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIER1→partner) and Y-score (partner→MIER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DR1 →	+0.375	+0.353	.005	.001	3	5
OV	TRAP1 →	-0.635	-0.536	<.001	<.001	3	5
BRCA	SERPINB8 →	+0.598	+0.554	<.001	.001	3	4
OV	NARS2 →	-0.638	-0.520	.002	<.001	3	4
BRCA	MRPL44 →	-0.357	-0.602	<.001	<.001	3	4
BRCA	MRPS10 →	-0.320	-0.402	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,417 associations by consensus.

Exploration

MIER1 survival (RNA) · tumor vs normal (RNA) · all MIER1 data types