MIEN1

Across TCGA patient cohorts, MIEN1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,268 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MIEN1-associated genes across cancer lineages are ERBB2, MAP3K6, and SLC12A4. Each is linked with MIEN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIEN1-to-partner and partner-to-MIEN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIEN1 versus ERBB2 in BRCA, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIEN1→partner) and Y-score (partner→MIEN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ERBB2 →	+1.446	+0.915	<.001	<.001	3	4
BRCA	MAP3K6 →	-1.023	-1.106	<.001	<.001	3	4
BRCA	SLC12A4 →	-0.537	-0.809	.002	<.001	3	4
UCEC	PRDX6 →	+0.380	+0.360	.006	.005	3	3
CCRCC	UBE2V1P15 →	-0.845	-0.246	<.001	.004	3	3
OV	CLEC11A →	-0.931	-0.350	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,268 associations by consensus.

MIEN1 vs ERBB2 — BRCA

Explore this scatter interactively →