MIEF2

Across TCGA patient cohorts, MIEF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,361 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MIEF2-associated proteins across cancer lineages are MLKL, EPN2, and LLGL1. Each is linked with MIEF2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIEF2-to-partner and partner-to-MIEF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIEF2 versus MLKL in LSCC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIEF2→partner) and Y-score (partner→MIEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MLKL →	-0.534	-0.568	<.001	<.001	3	5
BRCA	EPN2 →	+0.507	+0.794	<.001	<.001	3	5
LSCC	LLGL1 →	+0.262	+0.451	<.001	<.001	3	5
BRCA	RPL23A →	-0.266	-0.490	<.001	.001	3	4
BRCA	RPSA →	-0.169	-0.482	<.001	<.001	3	4
LSCC	SMG6 →	+0.250	+0.532	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,361 associations by consensus.

MIEF2 vs MLKL — LSCC

Explore this scatter interactively →