MIEF2

Across TCGA cell cohorts, MIEF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,784 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MIEF2-associated GO terms across cancer lineages are Vacuole organization, Positive regulation of autophagy, and Macroautophagy. Each is linked with MIEF2 in more than 14 cancer types. Because this analysis shows association rather than direction, both MIEF2-to-partner and partner-to-MIEF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by MIEF2-low versus MIEF2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIEF2→partner) and Y-score (partner→MIEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vacuole organization →	+0.070	+1.487	.001	<.001	3	15
STOMACH	Positive regulation of autophagy →	+0.059	+1.345	.001	<.001	3	15
STOMACH	Macroautophagy →	+0.086	+1.550	<.001	<.001	3	15
STOMACH	Negative regulation of autophagy →	+0.079	+1.026	.002	.002	3	14
STOMACH	Endosomal transport →	+0.069	+1.178	<.001	<.001	3	14
STOMACH	Process utilizing autophagic mechanism →	+0.092	+1.678	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,784 associations by consensus.

Vacuole organization by MIEF2 expression — STOMACH

Explore this box plot interactively →