MID2

Across TCGA patient cohorts, MID2 mutation is significantly associated with the RNA expression of many other genes, with 3,784 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MID2-associated genes across cancer lineages are SLC20A1P3, RNA5SP138, and NMRAL1. Each is linked with MID2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MID2-to-partner and partner-to-MID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC20A1P3 grouped by MID2-low versus MID2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MID2→partner) and Y-score (partner→MID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SLC20A1P3 →	+0.051	+4.595	.009	.004	3	3
UCEC	RNA5SP138 →	+0.215	+2.366	<.001	.006	3	3
UCEC	NMRAL1 →	+0.259	+2.763	.009	.002	3	2
UCEC	C1orf50 →	+0.282	+3.353	<.001	<.001	3	2
UCEC	DAPK3 →	+0.516	+2.754	<.001	<.001	3	2
UCEC	CHAF1A →	+0.756	+3.108	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,784 associations by consensus.

SLC20A1P3 by MID2 expression — COAD

Explore this box plot interactively →