MID1IP1

Across TCGA patient cohorts, MID1IP1 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MID1IP1-associated genes across cancer lineages are ATM, EGFR_pY1068, and ERK2. Each is linked with MID1IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MID1IP1-to-partner and partner-to-MID1IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by MID1IP1-low versus MID1IP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MID1IP1→partner) and Y-score (partner→MID1IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.754	-3.700	<.001	.001	3	2
UCEC	EGFR_pY1068 →	-0.288	-2.321	.006	.034	3	1
UCEC	ERK2 →	+0.214	+1.700	.008	.044	3	1
UCEC	FASN →	+0.354	+2.906	.034	.001	3	1
UCEC	ACC_pS79 →	+0.311	+1.700	.034	.044	3	1
UCEC	Heregulin →	-0.110	-2.321	.036	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

ATM by MID1IP1 expression — UCEC

Explore this box plot interactively →