MID1

Across TCGA patient cohorts, MID1 mutation is significantly associated with the RNA expression of many other genes, with 4,160 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MID1-associated genes across cancer lineages are OR4H12P, PSMF1, and FTLP18. Each is linked with MID1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MID1-to-partner and partner-to-MID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4H12P grouped by MID1-low versus MID1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MID1→partner) and Y-score (partner→MID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR4H12P →	+0.025	+5.225	<.001	.001	3	3
UCEC	PSMF1 →	+0.221	+3.010	.003	<.001	3	3
STAD	FTLP18 →	+0.122	+4.691	.001	.003	3	3
LUAD	RN7SL120P →	+0.143	+5.315	<.001	<.001	3	3
LUSC	RNU6-655P →	+1.063	+7.924	<.001	.008	3	3
BRCA	RN7SL386P →	+0.078	+4.649	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,160 associations by consensus.

OR4H12P by MID1 expression — SKCM

Explore this box plot interactively →