MICU3

Across TCGA cell cohorts, MICU3 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MICU3-associated genes across cancer lineages are LYZL1, LYZL4, and C9orf92. Each is linked with MICU3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MICU3-to-partner and partner-to-MICU3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LYZL1 grouped by MICU3-low versus MICU3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICU3→partner) and Y-score (partner→MICU3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LYZL1 →	+0.027	+5.569	<.001	.001	3	1
BLOOD_Leukemia	LYZL4 →	+0.080	+4.152	<.001	.009	3	1
BLOOD_Leukemia	C9orf92 →	+0.063	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR2A2 →	+0.019	+4.969	<.001	.003	3	1
LUNG_NSCLC_LUAD	RETN →	+0.102	+4.949	<.001	<.001	3	1
LUNG_NSCLC_LUAD	ASB10 →	+0.009	+3.604	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

LYZL1 by MICU3 expression — BLOOD_Leukemia

Explore this box plot interactively →