MICU2

Across TCGA cell cohorts, MICU2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,873 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MICU2-associated GO terms across cancer lineages are Protein localization to chromosome, centromeric region, Mitochondrial translational termination, and Positive regulation of chromosome separation. Each is linked with MICU2 in more than 12 cancer types. Because this analysis shows association rather than direction, both MICU2-to-partner and partner-to-MICU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome, centromeric region grouped by MICU2-low versus MICU2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MICU2→partner) and Y-score (partner→MICU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein localization to chromosome, centromeric region →	+0.152	+0.965	<.001	<.001	3	13
LUNG_SCLC	Mitochondrial translational termination →	+0.109	+0.733	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromosome separation →	+0.144	+0.787	.001	.003	3	12
BONE	Sister chromatid biorientation →	+0.117	+0.546	<.001	<.001	3	12
BLOOD_Leukemia	Positive regulation of mRNA 3'-end processing →	+0.109	+0.542	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of chromosome segregation →	+0.118	+0.596	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,873 associations by consensus.

Protein localization to chromosome, centromeric region by MICU2 expression — SOFT_TISSUE

Explore this box plot interactively →