MICU2

Across TCGA cell cohorts, MICU2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MICU2-associated genes across cancer lineages are TBC1D21, C12orf40, and OR2V1. Each is linked with MICU2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MICU2-to-partner and partner-to-MICU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D21 grouped by MICU2-low versus MICU2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICU2→partner) and Y-score (partner→MICU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	C12orf40 →	+0.009	+3.684	<.001	.006	3	1
LARGE_INTESTINE	OR2V1 →	+0.034	+4.510	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TBC1D21 by MICU2 expression — LARGE_INTESTINE

Explore this box plot interactively →