MICU1

Across TCGA cell cohorts, MICU1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,641 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MICU1-associated GO terms across cancer lineages are Cellular response to calcium ion starvation, Protein localization to endosome, and Regulation of glycolytic process through fructose-6-phosphate. Each is linked with MICU1 in more than 14 cancer types. Because this analysis shows association rather than direction, both MICU1-to-partner and partner-to-MICU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to calcium ion starvation grouped by MICU1-low versus MICU1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MICU1→partner) and Y-score (partner→MICU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cellular response to calcium ion starvation →	+0.181	+0.772	<.001	<.001	3	15
BONE	Protein localization to endosome →	+0.171	+0.648	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of glycolytic process through fructose-6-phosphate →	+0.105	+0.662	<.001	<.001	3	10
LARGE_INTESTINE	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.105	+0.662	<.001	<.001	3	10
LARGE_INTESTINE	Regulation of smoothened signaling pathway →	+0.038	+0.629	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.144	+1.362	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,641 associations by consensus.

Cellular response to calcium ion starvation by MICU1 expression — BLOOD_Leukemia

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