MICOS10

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MICOS10 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MICOS10-associated genes across cancer lineages are CD4+ Tem. Each is linked with MICOS10 in more than 1 cancer types. Because this analysis shows association rather than direction, both MICOS10-to-partner and partner-to-MICOS10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by MICOS10-low versus MICOS10-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICOS10→partner) and Y-score (partner→MICOS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCD4+ Tem →+0.020+6.623<.001.01931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tem by MICOS10 expression — HNSC

Box plot of CD4+ Tem in MICOS10-low vs MICOS10-high samples in HNSC.

Explore this box plot interactively →

Exploration