MICD

Across TCGA patient cohorts, MICD RNA expression is significantly associated with the go_rna of many other GO terms, with 6,573 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MICD-associated GO terms across cancer lineages are Protein modification by small protein removal, Protein polyubiquitination, and Regulation of nucleobase-containing compound transport. Each is linked with MICD in more than 24 cancer types. Because this analysis shows association rather than direction, both MICD-to-partner and partner-to-MICD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein modification by small protein removal grouped by MICD-low versus MICD-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MICD→partner) and Y-score (partner→MICD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Protein modification by small protein removal →	+0.050	+0.799	<.001	<.001	3	24
LAML	Protein polyubiquitination →	+0.052	+1.047	<.001	<.001	3	24
THYM	Regulation of nucleobase-containing compound transport →	+0.080	+0.320	<.001	<.001	3	24
STAD	Receptor metabolic process →	+0.053	+0.312	<.001	<.001	3	24
STAD	Protein targeting to vacuole →	+0.057	+0.270	<.001	<.001	3	23
DLBC	Vacuolar transport →	+0.050	+0.449	.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,573 associations by consensus.

Protein modification by small protein removal by MICD expression — LAML

Explore this box plot interactively →