Across TCGA patient cohorts, MICB mutation is significantly associated with the RNA expression of many other genes, with 983 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MICB-associated genes across cancer lineages are SRIP2, DHFRP5, and ARF4P4. Each is linked with MICB in more than 2 cancer types. Because this analysis shows association rather than direction, both MICB-to-partner and partner-to-MICB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICB→partner) and Y-score (partner→MICB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	SRIP2 →	+0.302	+4.591	<.001	.004	3	3
SKCM	DHFRP5 →	+0.089	+4.411	<.001	.005	3	2
HNSC	ARF4P4 →	+0.112	+5.182	<.001	.007	3	2
UCEC	TARBP1 →	-0.618	-2.896	.003	.002	3	2
SKCM	RNU1-108P →	+0.251	+2.678	<.001	.007	3	2
LUAD	RNU6-1137P →	+0.797	+5.217	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 983 associations by consensus.

Exploration

MICB survival (RNA) · tumor vs normal (RNA) · all MICB data types