Across TCGA cell cohorts, MICB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,452 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MICB-associated GO terms across cancer lineages are Negative regulation of defense response to virus by host, Negative regulation of defense response to virus, and T cell activation involved in immune response. Each is linked with MICB in more than 13 cancer types. Because this analysis shows association rather than direction, both MICB-to-partner and partner-to-MICB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MICB→partner) and Y-score (partner→MICB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of defense response to virus by host →	+0.172	+1.250	<.001	<.001	3	14
KIDNEY	Negative regulation of defense response to virus →	+0.114	+1.299	<.001	.004	3	12
LUNG_SCLC	T cell activation involved in immune response →	+0.115	+2.292	<.001	<.001	3	11
LARGE_INTESTINE	Positive regulation of mitotic cell cycle phase transition →	+0.057	+1.255	<.001	<.001	3	10
CNS	Positive regulation of cell cycle process →	+0.062	+1.167	<.001	.002	3	10
CNS	Positive regulation of cytokinesis →	+0.070	+1.121	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,452 associations by consensus.

Exploration

MICB survival (RNA) · tumor vs normal (RNA) · all MICB data types