MICALL1

Across TCGA patient cohorts, MICALL1 mutation is significantly associated with the RNA expression of many other genes, with 2,107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MICALL1-associated genes across cancer lineages are PARD6G, OR5AC1, and RNU6-486P. Each is linked with MICALL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MICALL1-to-partner and partner-to-MICALL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PARD6G grouped by MICALL1-low versus MICALL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICALL1→partner) and Y-score (partner→MICALL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PARD6G →	+0.532	+3.625	.005	.001	3	3
LGG	OR5AC1 →	+0.038	+4.760	<.001	.006	3	3
HNSC	RNU6-486P →	+0.252	+6.132	<.001	.001	3	2
BLCA	RPS14P5 →	+0.123	+2.828	<.001	.004	3	2
SKCM	RN7SL255P →	+0.354	+2.031	<.001	.008	3	2
SKCM	RN7SL392P →	+0.052	+3.594	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,107 associations by consensus.

PARD6G by MICALL1 expression — UCEC

Explore this box plot interactively →